1、JKE-1674基本信息：

Purity Specification: ≥98%

Molecular Formula :C20H20CL2N4O4

CAS Number: 2421119-60-8 Formula Weight : 451.3 Storage:-20°C Stability: ≥2 years

JKE-1674 is supplied as a crystalline solid. A stock solution may be made by dissolving the JKE-1674 in the solvent of choice, which should be purged with an inert gas. JKE-1674 is soluble in DMSO.

JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4) and an active metabolite of the GPX4 inhibitor ML-210 (Item No. MED24563). JKE-1674 reduces viability of LOX-IMVI cancer cells (EC50 =0.03 μM) and in a panel of additional cancer cell lines, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 (Item No. MED14798).

2、JKE-1674物理化学性质：

3、JKE-1674英文别名：